Inhibition of 3,3′,4,4′,5-Pentachlorobiphenyl-Induced Chicken Embryotoxicity by 2,2′,4,4′,5,5′-Hexachlorobiphenyl

Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate

Objective Methotrexate (MTX), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive system in mice. The aim of this research was to study the effects of ethyl pyruvate (EP) on embryo development and oxidative stress changes in the testis of mice treated with MTX. MaterialsAndMethods In this experimental study, thirt...

Inhibition of Eimeria acervulina Sporozoite Invasion by Rabbit and Chicken Antisera Using ISI Assay

Embryotoxicity Caused by DON-Induced Oxidative Stress Mediated by Nrf2/HO-1 Pathway

Deoxynivalenol (DON) belongs to the type B group of trichothecenes family, which is composed of sesquiterpenoid metabolites produced by Fusarium and other fungi in grain. DON may cause various toxicities, such as cytotoxicity, immunotoxicity, genotoxicity as well as teratogenicity and carcinogenicity. In the present study, we focus on a hypothesis that DON alters the expressions of Nrf2/HO-1 pa...

attenuation of cyclosporine-induced sperm impairment and embryotoxicity by crataegus monogyna fruit aqueous extract

objective: cyclosporine (cs), a cyclic undecapeptide with potent immunosuppressive activity, causes several adverse effects including reproductive toxicity. this study aims to examine the ability of crataegus monogyna aqueous fruit extract as an antioxidant to protect against cs-induced reproductive toxicity. materials and methods: in this experimental study, 32 adult male wistar rats were divi...

attenuation of methotrexate-induced embryotoxicity and oxidative stress by ethyl pyruvate

objective: methotrexate (mtx), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive system in mice. the aim of this research was to study the effects of ethyl pyruvate (ep) on embryo development and oxidative stress changes in the testis of mice treated with mtx. materials and methods: in this experimental study, t...